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After co-culturing with MSC-derived microvesicles, increased levels of M2 markers and fewer LPS-induced pro-inflammatory cytokines were detected in BV-2 cells, indicating their role in the phenotypic transition from M1 to M2 (163)
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Most likely, given consistent beneficial effects, BPC 157 therapy could specifically counteract the cytotoxic and damaging actions of NO, being organ-specific
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